منابع مشابه
The microRNA world: small is mighty.
A new paradigm of RNA-directed gene expression regulation has emerged recently, profound in scope but arresting in the apparent simplicity of its core mechanism. Cells express numerous small ( approximately 22 nucleotide) RNAs that act as specificity determinants to direct destruction or translational repression of their mRNA targets. These small RNAs arise from processing of double-stranded RN...
متن کاملThe Simplex Algorithm is NP-mighty
We propose to classify the power of algorithms by the complexity of the problems that they can be used to solve. Instead of restricting to the problem a particular algorithm was designed to solve explicitly, however, we include problems that, with polynomial overhead, can be solved ‘implicitly’ during the algorithm’s execution. For example, we allow to solve a decision problem by suitably trans...
متن کاملThe mighty mite
storehouses of terrestrial biodiversity, but many of the more astounding species are apparent only after the closest scrutiny. Here are a few of the roughly 2000 species of mite (Arachnida: Acari) that can be found in the subtropical rainforests of Lamington National Park in southeast Queensland, Australia. The mites there range in size from 0.182 millimetres to 7 millimetres, with the minute b...
متن کاملMicroexons--tiny but mighty.
The landscape of alternative splicing is only beginning to unravel, and the functional consequences are often unclear. Two articles in Cell and Genome Research focus on a set of largely ignored yet highly conserved exons, microexons. These appear strongly regulated by RNA-binding proteins (RBPs) and functionally modulate protein–protein interactions with strong evidence for deregulation in auti...
متن کاملCod all mighty
The importance of fish in the history of Europe, particularly in Catholic countries, and the European colonisation of North America, have been underplayed, according to a new book by University of California anthropologist, Brian Fagan. Most Americans have been traditionally schooled to believe that the European discovery and settlement of the New World arose from two events: the first voyage o...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2003
ISSN: 0923-7534
DOI: 10.1093/annonc/mdg309